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Killing Bacteria Wipes Out Regenerative Cells

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Killing Bacteria Wipes Out Regenerative Cells In regenerative medicine, there is always a reason for failure. When a bone graft fails and we do not understand why, we are destined to keep on failing. The only way to improve in the clinic is to study our failures until we find the cause. Each time we find the cause, we become better clinicians with more predictable results. The following case is an example of what we have been preaching for years: Anything you do locally to kill bacteria will wipe out the regenerative cells. Bacteria are much harder to kill than…

Why Is Vertical Augmentation Difficult?

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Why Is Vertical Augmentation Difficult? Recently, we released our custom 3D-printed pure beta tricalcium phosphate bone grafts for lateral ridge augmentation. Through 10 years of R&D, we are finally at a point where lateral ridge augmentation is as predictable as a composite restoration. However, vertical ridge augmentation is completely different and leads to the question at the title of this article. The first question we need to answer is this: Why do we lose bone after extraction? The answer to that question is easy: operator negligence. After the extraction, the operator performed half of the surgery. Nowhere else in the…

Journal of Periodontology: Congratulations and a Criticism

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Journal of Periodontology:Congratulations and a Criticism We would like to congratulate Dr. Effie Ioannidou and the Journal of Periodontology. Since she has taken over one year ago, the journal has seen significant improvements, but before we discuss her work, we need to understand the situation she took over. Here at SteinerBio we have been studying bone grafts for 20 years and we recognize fake science in our field. As fake science has flourished in our field for years, we questioned if other areas of fake science existed in the Journal of Periodontology. The previous editor of the journal formed a…

Treating Implant Bone Loss

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Treating Implant Bone Loss An accurate diagnosis is required for a positive treatment outcome. In our last post, we discussed how periimplantitis is not possible in sites grafted with cadaver bone grafts. However actual periimplantitis is also common. For these two very different lesions we need very different treatment protocols. Read more: Periimplantitis Is Impossible In Cadaver Bone Grafts In cadaver bone graft sites, the histologic description is sclerotic bone surrounded by inflamed perivascular tissue with a diagnosis of osteitis. Obviously, these cases have nothing to do with periimplantitis and treatment needs to modified accordingly to be successful. In periimplantitis,…

Periimplantitis Is Impossible In Cadaver Bone Grafts

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Periimplantitis Is Impossible In Cadaver Bone Grafts Our profession is struggling with a continuing increase in implant loss. Virtually every case is diagnosed as periimplantitis. In this post, we will begin to identify the different reasons for implant loss, starting with when bone loss around a dental implant is not periimplantitis. The first point to make is to clarify that implant failure is a misnomer. Implants don’t fail because it is the bone that fails. Implants are inert metals and have no biologic activity. Everything that happens from integration to loss of bone around an implant happens in the bone…

Fake Puros Studies

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Fake Puros Studies When talking to dentists about what bone graft material they use, we often hear that they use Puros because it has the most scientific support. We smile and do our best to maintain our composure. The last thing we want to do is to embarrass a fellow dentist by challenging his understanding of bone graft science. So, what did in this article is look at a few papers on Puros that are often quoted in support of this material. When we ask for the scientific support for placing implants in sockets grafted in allograft, the following paper…

No Membrane Contact Sinus Augmentation

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No Membrane Contact Sinus Augmentation Never tear another sinus membrane In a previous article, “Sinus Augmentation Without Sinus Membrane Exposure”, we described a method of performing a sinus augmentation without contacting the sinus membrane. That case discussed a minor sinus elevation (sinus bump). Today, we are using the same technique that allows the graft material to flow through the bone and lift the sinus membrane but with the ability to graft the sinus with any desired amount of graft material. The sinus presents with a septum (blue arrow) separating the sinus in two compartments. The patient wanted only one additional…

Alzheimer’s is a Prion Infection

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Alzheimer’s is a Prion Infection Prion Infections are Transmitted Through Cadaver Tissue Grafts and Surgical Instruments Many neurodegenerative diseases have been found to be prion infections.1,2 In this post, we will discuss what prions are, what human neurodegenerative diseases are caused by prions, and how the infections are transmitted. Prions are proteins that are produced in human cells that become misfolded. The misfolding of the protein does not occur randomly but can only take place when the normal protein is induced to change shape by another misfolded protein. They retain the chemical components of the normal protein and it is…

An Orthopedic Pain Med for Dental Implantologists

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An Orthopedic Pain Med for Dental Implantologists For pain control in dentistry, we deal with pain from periodontal therapy, endodontic therapy, and implant therapy. These surgeries deal with different tissues and these tissues are likely to respond differently to different pain medications. However, orthopedic surgeons and dental implantologists both work primarily with bone, and we can benefit from sharing information on the types of pain meds that best benefit our patients after skeletal surgery. One pain medication that is popular with orthopedic surgeons but is seldom used by implantologists is diclofenac. First synthesized in 1973, diclofenac is the most prescribed…

Severe Lesion, Delayed Growth

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Severe Lesion, Delayed Growth At age 2, the following patient suffered trauma to her lower jaw. At age 12, a significant lesion was found in her mandibular symphysis. The diagnosis was a traumatic bone cavity (previously called a traumatic bone cyst). In 2016 at age 12, the lesion was operated by a skilled oral surgeon as follows: The lower left image shows the lesion filled with mineralized freeze-dried bone allograft. The lower middle image shows the graft covered with a particulate allograft in a polymer designed to function as a barrier. In 2020, the area was rescanned, and the radiologist…